"Study of Metabolic Syndrome and Its Components Among Kurnool District Population of Andhra Pradesh with Different Ethnic Backgrounds."

Abstract

Background: There is a constant increase in the preponderance of cardiovascular diseases in India. The recent scientific evidences have shown that if you do not detect and treat the metabolic syndrome patients at an early stage, it may proceed to cardiovascular disease. A scientific data on pattern of metabolic syndrome components of a population is very essential to formulate the preventive and treatment modalities among them. Aim: To explore the prevalence of metabolic syndrome and its components among Kurnool district population of Andhra Pradesh with different ethnic background. Method: A total of 1032 (344 subjects in each group) participants of 20-60 years of age group were analyzed for MetS. A modified NCEP ATP III criterion was applied for this. From each group 20 subjects were analyzed for fasting serum insulin and HOMA-IR randomly. Results: Overall prevalence of metabolic syndrome was found to 31.97%. It was almost equally prevalent among men (32.82%) and women (30.87%). Urban population (42.15%) were found to be highly inflicted by metabolic syndrome than rural (31.97%) and tribal (21.80%). Decreased HDL (78.87%) followed by increased waist circumference (57.84%) and hypertriglyceridemia (31.78%) were found to be the preceding risk factors of Mets in all the groups. The lipid estimates were not in correlation with insulin resistance (by HOMA IR) in rural population. Tribal women were found to be having a slightly higher mean waist circumference (86.45cm) compared to rural women (85.87cm). The behavioural cardiovascular risk factors like smoking alcohol consumption decreased circadian physical activity were high in rural and tribal population compared to urban population. Whereas other physiological cardiovascular risk factors like family history of hypertension and diabetes of rural population were in concordance to urban population. Conclusion: Metabolic syndrome prevalence is very high in Kurnool district population. Mets components are highly prevalent among the individuals with low WC (Waist Circumference) and BMI (Body Mass Index). This warrants the need to implement preventive strategies for Mets among the population of Kurnool district. The future projects has to be formulated with an aim to find out the genetic factors behind this scenario.