Journal Article Publications

Succeed early: Early initiation of breastfeeding: A prospective observational study

2026-08-18T10:24:56Z

Succeed early: Early initiation of breastfeeding: A prospective observational study Preeti Shankar Malapure1 . iD , Namita Gupta1 Ravindra Naganoor2 . iD , Rajasri G Yaliwal1* . iD , Santhoshi Dantapuram1,

On-Demand Acetaminophen Versus Scheduled Diclofenac-Serratiopeptidase After Cesarean Delivery: A Randomized Controlled Trial

2026-08-18T10:19:12Z

On-Demand Acetaminophen Versus Scheduled Diclofenac-Serratiopeptidase After Cesarean Delivery: A Randomized Controlled Trial Rajasri G. Yaliwal , Devineni N. Sree , Ambika H. K. , Shreedevi Kori 1 1

Laparoscopic deroofing of a recurrent non‐parasitic splenic cyst in a paediatric patient: A case report and review of literature

2026-08-05T12:08:26Z

Laparoscopic deroofing of a recurrent non‐parasitic splenic cyst in a paediatric patient: A case report and review of literature Vijaya L Patil, Deepak Chavan, Santosh Madagond, Vikram Sindagikar, Babugouda Nyamannawar, Akshata Goudar, M. Hemanth Reddy, Linette Mathias Splenic cysts are uncommon lesions, often discovered incidentally during imaging studies. Recurrent splenic cysts pose a clinical challenge due to their potential for complications such as rupture, haemorrhage or infection. Management options range from observation and percutaneous drainage to partial or total splenectomy. Laparoscopic deroofing has emerged as a minimally invasive, spleen‐preserving approach with favourable outcomes, although recurrence remains a concern, particularly in incompletely excised cysts. This report presents a rare case of recurrent non‐parasitic splenic cyst that was successfully managed by laparoscopic deroofing. This case highlights the clinical utility of laparoscopic deroofing as a safe, spleen‐conserving minimal invasive surgical option for recurrent splenic cysts. It offers reduced morbidity, faster recovery and lower risk of post‐splenectomy complications. While the risk of recurrence persists, meticulous surgical technique and careful patient selection can optimise the outcomes. A literature review supports laparoscopic deroofing as an effective strategy in managing selected cases of recurrent splenic cysts with low complication and recurrence rates.

CTLA‐4 Gene Polymorphism in Pediatric Type 1 Diabetes Mellitus: A Case–Control Study

2026-08-05T11:28:33Z

CTLA‐4 Gene Polymorphism in Pediatric Type 1 Diabetes Mellitus: A Case–Control Study Thammineni Aniketh, Raghavendra Gobbur, Gurushantappa S. Kadakol Objective: To analyze the relationship between CTLA‐4 (+49A/G) polymorphism and pediatric type 1 diabetes mellitus (T1DM). Materials and Methods: The observational case–control study was done for 18 months in 44 children (1–16 years of age), 22 of whom had T1DM and 22 controls, were included. CTLA‐4 (+49A/G) gene polymorphism was analyzed using polymerase chain reaction‐restriction fragment length polymorphism and validated by Sanger sequencing. Various clinical, anthropometric, and biochemistry variables were documented. Results: The cases and controls were similar in terms of age, gender distribution, family history of diabetes, and consanguinity. The average hemoglobin A1c values were higher in case groups compared to controls (12.41% ±3.09% vs. 4.21 ± 0.5%; P < 0.001). The CTLA4 (+49A/G) gene showed higher frequencies of the G/G genotype in cases compared to controls(54.55% vs. 22.73%; P = 0.030), whereas A/A was found to be higher in controls (P = 0.014). The frequency of the G allele in cases (0.66) was higher than in controls (0.32). The G/G genotype showed higher prevalence in the case group at a younger age, and siblings of offspring showed clustering of the G/G genotype. Conclusion: In particular, the G/G genotype of the CTLA‐4 + 49A/G polymorphism was found to be significantly associated with T1DM in children and to influence the age of onset.