Faculty of Pharmacology

Optimization of Topical Glucocorticoid Therapy: A Prospective Observational Study Evaluating Formulation, Potency, and Clinical Outcomes in a Tertiary Care Hospital

2026-04-01T00:00:00Z

Optimization of Topical Glucocorticoid Therapy: A Prospective Observational Study Evaluating Formulation, Potency, and Clinical Outcomes in a Tertiary Care Hospital Sreeraj G, Shrinivas R. Raikar, Sneha Background: Dermatological disorders contribute significantly to global morbidity and often require prolonged management. Topical glucocorticoids are widely used as first-line therapy, with treatment outcomes influenced by both formulation and pharmacological potency. Objective: To evaluate the prescribing pattern of topical glucocorticoids with respect to formulation, potency, and associated clinical outcomes in a tertiary care setting. Methods: A prospective observational study was conducted in the dermatology outpatient department of a tertiary care hospital. A total of 303 prescriptions containing corticosteroids were analyzed. Data were evaluated using descriptive statistics, and the Chi-square test was applied to assess the association between diagnosis and potency selection. Results: Creams and ointments were the most frequently prescribed formulations. Very high potency corticosteroids accounted for 48.2% of prescriptions, followed by high potency agents (36.3%). Good to excellent clinical improvement was observed in 79.2% of patients. Adverse effects were not reported in 51.8% of cases, while skin atrophy was the most common adverse event. A statistically significant association was found between dermatological diagnosis and potency selection (p < 0.05). Conclusion: Topical glucocorticoids demonstrate high therapeutic effectiveness; however, rational selection of potency and formulation is essential to optimize clinical outcomes and minimize adverse effects.

EVALUATION OF CONCEPT OF ANTIMICROBIAL STEWARDSHIP AMONG UG MEDICAL STUDENTS FOR BETTER UNDERSTANDING OF USE OF ANTIMICROBIAL AGENTS AND MINIMIZING ANTIMICROBIAL RESISTANC

2024-01-01T00:00:00Z

EVALUATION OF CONCEPT OF ANTIMICROBIAL STEWARDSHIP AMONG UG MEDICAL STUDENTS FOR BETTER UNDERSTANDING OF USE OF ANTIMICROBIAL AGENTS AND MINIMIZING ANTIMICROBIAL RESISTANC Patil, Jyoti S Objectives: The objective of this study is to assess interns perception and knowledge about antibiotic stewardship and their preparedness for appropriate use of antimicrobials and to prescribe antimicrobials. Methods: The 164 medical interns of BLDE (DU)’s Shri B.M. Patil Medical College who provided consent to participate in the study were included in this cross-sectional web-based online survey. The study was carried out using a validated questionnaire. The data were analyzed using the statistical tool for the social sciences (Version 20). Results: Out of the 164 interns, 133 (83.1%) completed the entire survey. The term “antimicrobial stewardship” was familiar to 51% (n=68). 50% (n=66) agreed that antibiotics are inappropriately used at the hospital. Approximately 88% (n=104) and 85% (n=113) of the interns thought that insufficient infection control practices and the use of wide spectrum antibiotics were the main causes of resistance development, respectively. About 90% (n=119) thought that lecture series and grand round discussions on the responsible use of antibiotics were good educational tools. About 37% (n=49), 41% (n=54), and 24% (n=32) of the interns understood the proper antibiotic selection for treating simple cases of urinary tract infections, could de-escalate antibiotic therapy, understand an anti-biogram, and could match a different combination of antimicrobials and microorganisms, respectively. Conclusion: The major findings of our study were, despite students having good perception, the knowledge component was inadequate, that is, they lacked their preparedness and confidence to prescribe antibiotics which emphasizes that the students are aware of the antimicrobial stewardship but their knowledge domain needs to be improved for better application in their clinical practice.

Analysis of Prescribing Practices in the Dermatology Outpatient Department of a Tertiary Care Teaching Hospital.

2023-01-01T00:00:00Z

Analysis of Prescribing Practices in the Dermatology Outpatient Department of a Tertiary Care Teaching Hospital. Bapugouda Patil, Jyoti Patil, Leela Hugar, Gurudatta Moharir.

Competency‑Based Medical Education: Perception and Challenges among Students.

2023-01-01T00:00:00Z

Competency‑Based Medical Education: Perception and Challenges among Students. Jyoti S Patil, S Latha, Vijaya Patil, Leela Hugar.