Clinico – Hematological Analysis of Pancytopenia: A Bone Marrow Study.

Abstract

Pancytopenia is characterized by anemia, leucopenia and thrombocytopenia, a common hematological problem. It is a striking feature of many serious and life threatening illnesses. The disease pattern varies in different population groups, in age pattern, nutritional status and prevalence of infective disorder. Present study was conducted to assess the etiology, clinical profile and bone marrow morphology of pancytopenia. Objective: To know various patterns of clinical presentation and co-relate hematological parameters and bone marrow study with clinical findings, in differentiating causes of pancytopenia. Methods: A two-years study from January 2009 to December 2010 was conducted in Department of Pathology. Total 106 pancytopenia patients aged 15-65 years were studied to determine their clinical features, peripheral smear study and bone marrow morphology. The etiological pattern was assessed through relevant investigations done on the respective patients.