Abstract:
Chronic fissure in Ano is a common benign anal disease. The pain associated with it may affect the
quality of life. Morbidity associated with surgical treatment of Chronic Anal Fissure has led to the
increasing use of pharmacological agents. The present study was undertaken to test the efficacy of
topical 2% Diltiazem and compare it with Internal Sphincterotomy in context with effectiveness, side
effects and complications. 70 patients with chronic anal fissure were enrolled for the study and were
divided into two groups.