Abstract:
Use of immunohistochemical technique is increasing in diagnosing various diseases. In many situations it may not be
possible to differentiate entities with overlapping clinical and histopathological features. Immunostaining of cellular
antigens is immensely helpful in such cases. Immunohistochemistry (IHC) has also been in use for targeted cancer
therapy. In this article, the discussion will be restricted to use of IHC in dermatological disorders and use of classical
antigens with brief updating of some important newly discovered antigens