Abstract:
A scar is a fibrous tissue replacement that develops as a consequence of healing at the site of a prior ulcer or wound. Cutaneous scarring is a macroscopic disturbance of the normal structure and function of the skin architecture manifesting itself as an elevated or depressed area, with an alteration of skin texture, color, vascularity, nerve supply and biomechanical properties. [1]
Histologically, dermal scars are characterized by thickened epidermis with a flattened dermo-epidermal junction and an abnormal organization of the dermal matrix into parallel bundles of scar tissue collagen, as opposed to the normal basket weave pattern of dermal collagen. Scar collagen
