Abstract:
Xeroderma pigmentosum (XP) is characterized by hypersensitivity to sunlight, ocular
involvement, and progressive neurological complications. These manifestations are
due to a cellular hypersensitivity to ultraviolet radiation leading to a defect in repair
of DNA by the process of nucleotide excision repair. Basal cell carcinoma which is
rare in children can occur with XP. Though the XP induced changes are predominately
dermatologic, pose several challenges in anaesthetic management. Hence, we are
reporting a 9-year-old child with XP scheduled for excision of basal cell carcinoma
under general anaesthesia.
