Comparitive Study Of Pterygium Excision With Bare Sclera With Intraoperative 0.02% Mitomycin-C Versus Pterygium Excision With Conjunctival Autograft

Abstract

Background and objectives: Primary pterygium is one of the most common disorders seen in our community because the inhabitants have a high exposure to ultraviolet light. India, a tropical country where heat and dust are an environmental synonym, is an ideal home for pterygium. But recurrence after excision of pterygium is a common problem and various techniques have been used to reduce its recurrence rates. This study was undertaken to compare the outcome and recurrence rate after excision with bare sclera with 0.02% intraoperative mitomycin C application and conjunctival limbal autograft.

Methods: A prospective study was done which included 45 patients who attended the ophthalmology out patient department of Shri. B.M.Patil Medical College, Hospital and Research Centre during the study period. Patients were selected alternatively and numbered. Patients with even numbers underwent pterygium excision with 0.02% intra operative mitomycin- C application and patients with odd numbers underwent excision with conjunctival limbal autograft. The surgeries were done in Shri. B. M. Patil Medical College, hospital and research centre. All patients were followed up on post operative day 1, day 7, 1 month, 3 months and 6 months for recurrence and possible side effects of mitomycin C and graft complications.

Results: In the patients treated with bare sclera excision with intraoperative 0.02% mitomycin C, 1 case ( 4.5%) had recurrence, in the patients treated with conjunctival ix

limbal autograft 1 case (4.3% ) had recurrence and 1 patient had sclera thinning following intraoperative 0.02% mitomycin- C. Conclusion: To reduce the recurrence rate after pterygium excision both the procedures intraoperative mitomycin- C and the conjunctival limbal autograft are eqaully effective methods than bare sclera technique alone. Although both intraoperative mitomycin- C and conjunctival limbal autograft techniques are equally effective the latter is more safe and cost effective because of lesser complications