“A Comparative Study Of Inj.Bupivacaine 0.5% And Inj.Ropivacaine 0.5% For Supraclavicular Brachial Plexus Block”

Abstract

BACKGROUNDS AND OBJECTIVES Brachial plexus block at the supraclavicular level provides safe, effective, low cost anaesthesia with excellent post operative analgesia. The current study was an attempt to compare the effect of Inj.Bupivacaine 0.5% and Inj.Ropivacaine 0.5% in supraclavicular brachial plexus block for patients undergoing upper limb orthopedic surgeries with respect to onset of sensory blockade, onset of motor blockade, duration of sensory blockade, duration of motor blockade and any adverse effects were noted. MATERIALS AND METHODS The Present study entitled “A comparative study of Inj.Bupivacaine 0.5% and Inj.Ropivacaine 0.5% for supraclavicular brachial plexus block” was carried out in the Department of Anaesthesiology, B.L.D.E. University’s, Shri B.M. Patil Medical College Hospital and Research Centre, Vijayapur from October 2013 to June 2015. Each patient was randomly allocated to one of the two groups of 39 patients each. Group B – Bupivacaine group received 30 ml Bupivacaine 0.5% (5 mg/ml) Group R – Ropivacaine group received 30 ml Ropivacaine 0.5% (5 mg/ml) PARAMETERS The effect was studied with respect to onset of sensory blockade, onset of motor blockade, duration of sensory blockade, duration of motor blockade and any adverse effects were noted. RESULTS Onset of sensory block : In our study, we observed that onset of sensory block was earlier in Bupivacaine group (Group B) having a mean value of 16.6±3.2 minutes in comparison with Ropivacaine group (Group R) having a mean value of 19.9±4.0 minutes which was statistically significant. XII Onset of motor block : In our study, we observed that onset of motor block was earlier in Bupivacaine group (Group B) having a mean value of 21.4±2.6 minutes in comparison with Ropivacaine group (Group R) having a mean value of 25.9±2.4 minutes which was statistically significant. Duration of sensory block : In our study, we observed that duration of sensory block was longer in Bupivacaine group (Group B) having a mean value of 343.8±44.4 minutes in comparison with Ropivacaine group (Group R) having a mean value of 317.9±29.1 minutes which was statistically significant. Duration of motor block : In our study, we observed that duration of motor block was longer in Bupivacaine group (Group B) having a mean value of 387.4±36.0 minutes in comparison with Ropivacaine group (Group R) having a mean value of 368.7±33.1 minutes which was statistically significant. Variations in blood pressure, heart rate, SpO2, respiratory rate were statistically not significant in both the groups. No patient in our study developed any significant side effects. CONCLUSION Inj.Bupivacaine 0.5 % has early onset of sensory blockade, early onset of motor blockade, prolonged duration of sensory blockade, prolonged duration of motor blockade, when compared to Inj.Ropivacaine 0.5 % at equal volumes. Both the drugs maintain stable hemodynamic profile peri-operatively and are devoid of any adverse effects at the concentration and volumes used for the study