Abstract:
Lupus erythematosus (LE) is an autoimmune multisystem disorder with varied clinical manifestations. There are many
similarities and differences between pediatric and adult disease in regard to epidemiological, clinical and therapeutic
aspects. In general, the disease in children has a more aggressive course and need for prolonged treatment is frequent,
which implies a greater incidence of therapy‑related adverse effects. This review addresses various aspects of pediatric LE
and how they differ from or are similar to adult disease.
