Genetic and Molecular Profiling of GJB2 Gene in Deaf Mute Population of North Karnataka

Abstract

Hearing is a crucial component of human communication. Rarely its significance it is recognised until it is damaged or lost. The development of speech and language is impacted by hearing loss. The outer, middle, and inner ear are the three separate anatomical compartments that make up the human ear. The pinna, located on the outer ear, absorbs sound waves, and directs them into the ear canal, where they vibrate the ear drum. The three middle ear ossicles transport the vibrations as mechanical waves, which are then sent to the oval window of the inner ear where they are transformed into nerve impulses. The auditory nerve carries these impulses to the brain, where they are converted to sounds. Hearing impairment or hearing loss is a more accurate term for the inability to hear sounds