A Study Of Oral Glucose Tolerance In Pulmonary Tuberculosis

Abstract

Background and objectives The relation of pulmonary tuberculosis and development of altered OGT are not well documented and very few studies have reported that the incidence of diabetes mellitus in patients with pulmonary tuberculosis. The present study was aimed to find the incidence of glucose intolerance in patients with pulmonary tuberculosis. Methodology This one year cross sectional study was conducted in the Department of Medicine , Shri B M Patil Medical College , Vijayapur on patients with pulmonary tuberculosis. A total of 75 patients with patients with positive sputum smear for acid fast bacilli or chest x-ray features suggestive of pulmonary tuberculosis aged more than 30 years and less than 65 years were selected for the study. Results The results showed majority of the patients were males (84%) with maleto female ratio of 5.25:1. . The most commonest age group was 41-50 years (25.33%) followed by age >60 years (21.33%). The commonest presentation of pulmonary tuberculosis was cough and expectoration of sputum (100% each)followed by loss of appetite (96.67% ) followed by fever(76%). AFB findings showed +++ in 29.33% patients. On chest x-ray almost 60% of the patients had cavitatory lesions with infiltration . In 18.67% and 16% of patients fibrotic changes and cavitatory lesions without infiltration were noted. Conclusion and interpretation This study of 75 cases showed overall incidence of impaired glucose tolerance as 17.33% in patients with pulmonary tuberculosis. Among 82.67% patients GTT was normal (Fasting < 110 mg/dL and 2 hours < 140 mg/dL). In 13.33% of patients xii impaired glucose tolerance (Fasting < 126 mg/dL and 2 hours> 140 mg/dL) was recorded and among 4% patients diabetes mellitus (Fasting >126 mg/dL and 2 hours > 200 mg/dL) was diagnosed. No statistically significant association of sex, age and chest X-ray findings was seen in patients with pulmonary tuberculosis and diabetes mellitus.