Estimation of thyroid profile in patients with type 2 diabetes mellitus a comparative cross-sectional study

Abstract

BACKGROUND Diabetes mellitus and thyroid abnormalities are two most prevalent endocrinopathies. diabetes is one of the fastest growing noncommunicable metabolic syndrome. Thyroid dysfunction is a significant contributing factor to the poor glycaemic control observed in diabetes. In order to lower the risks of diabetes in the present and the future, it is imperative to improve thyroid function in both diabetic and non-diabetic patients and increase their resistance to the negative effects of thyroid diseases. Compared to non-diabetics, thyroid disease is more common in those with diabetes. Poor diabetes management is caused by aberrant thyroid hormone levels and abnormalities in thyroid function in diabetic patients. This is demonstrated in certain treated diabetics because it affects insulin resistance.

AIM To Estimate thyroid profile in Type 2 Diabetes mellitus patients. OBJECTIVES OF THE STUDY To determine relationship between type 2 diabetes mellitus and thyroid disorders and comparasion of their prevalance in both sexes. MATERIALS AND METHODS SOURCE OF DATA Patients admitted in the medicine ICU/WARDS OF BLDEUS Shri BM Patil medical college and Research Centre, Vijayapura and who fulfil the inclusion criteria. All investigations will be performed at the central lab of BLDEU’S Shri M Patil Medical College , Hospital and Research Centre, Vijayapura. METHOD OF COLLECTION OF DATA Type of study: COMPARATIVE CROSS-SECTIONAL STUDY DESIGN Sample size: 84 patient Using Statulator software for sample size calculation, Asuming the expected population standard deviation to be 11.9, and employing t-distribution to estimate sample size, the study would require a sample size of 84 to estimate a mean with 95% confidence and a precision of 2.6. CONCLUSION Serum T3, T4, and TSH levels were noticeably aberrant, and there was inadequate glycaemic regulation, according to our observations and results as well as comparisons with other research of a similar nature. Type 2 diabetics are more prone to have altered thyroid hormone levels, particularly in individuals with poor glycaemic control. If not adequately recognised, these changes in thyroid hormones may play a major role in the inadequate management of diabetes. A greater incidence of hypothyroidism was discovered by our investigation, especially in females. There was shown to be a moderate but substantial association between TSH and HbA1c. In order to improve medical care and lower morbidity, type 2 diabetic patients must have routine thyroid hormone testing.