Abstract:
The association between diabetes and thyroid dysfunction were first published
in 1979. Type 2 diabetes mellitus (T2DM) has an intersecting underlying pathology
with thyroid dysfunction. The literature is punctuated with evidence indicating a
contribution of abnormalities of thyroid hormones toT2DM.
Hyperthyroidism and hypothyroidism have been associated with insulin
resistance which has been reported to be the major cause of impaired glucose
metabolism in T2DM. The state-of-art evidence suggests a pivotal role of insulin
resistance in underlining the relation between T2DM and thyroid dysfunction