Abstract:
From times immemorial DIABETES is known to mankind with
increasing prevalence of diabetes globally, it is estimated that around 6.9 crore Indians are
diabetic next only to China, and with estimated 7.7 crore Indians have prediabetes. Trace
elements and their homeostasis are essential for various cellular metabolic reactions, and in
diabetes it is observed that trace elements are disrupted. Magnesium is an essential cofactor
of more than 300 enzymes and is a vital cofactor in enzymes involved in the glucose
metabolism. Magnesium has a role in production and action of insulin, and can also activate
insulin receptor tyrosine activity. It is reported that magnesium is deficient in diabetes
mellitus patients .