Abstract:
The ABO blood group system is arguably the best known, and yet
the most functionally mysterious, genetic polymorphism in humans. In the century since
their discovery, ABO antigen associations with infections and other diseases have been
the subject of hundreds of publications. Much new information has emerged since a
relationship between ABO and malaria was first suggested more than 40 years ago. There
is hypothesis that Plasmodium falciparum malaria has shaped the distribution of ABO
blood groups in humans. We aim to study the relationship between ABO blood groups
and severity of malaria.
