Abstract:
Background: Dermatological disorders contribute significantly to global morbidity and often require prolonged
management. Topical glucocorticoids are widely used as first-line therapy, with treatment outcomes influenced by
both formulation and pharmacological potency.
Objective: To evaluate the prescribing pattern of topical glucocorticoids with respect to formulation, potency, and
associated clinical outcomes in a tertiary care setting.
Methods: A prospective observational study was conducted in the dermatology outpatient department of a tertiary
care hospital. A total of 303 prescriptions containing corticosteroids were analyzed. Data were evaluated using
descriptive statistics, and the Chi-square test was applied to assess the association between diagnosis and potency
selection.
Results: Creams and ointments were the most frequently prescribed formulations. Very high potency corticosteroids
accounted for 48.2% of prescriptions, followed by high potency agents (36.3%). Good to excellent clinical
improvement was observed in 79.2% of patients. Adverse effects were not reported in 51.8% of cases, while skin
atrophy was the most common adverse event. A statistically significant association was found between dermatological
diagnosis and potency selection (p < 0.05).
Conclusion: Topical glucocorticoids demonstrate high therapeutic effectiveness; however, rational selection of
potency and formulation is essential to optimize clinical outcomes and minimize adverse effects.
